Consistent with observations made by others 21, otelixizumab\induced downmodulation of TCRs has important effects for the features of T lymphocytes while we have shown that it compromises the ability of antigen\dependent T cells to proliferate. manifestation of TCR on CD8+ … Continue reading Consistent with observations made by others 21, otelixizumab\induced downmodulation of TCRs has important effects for the features of T lymphocytes while we have shown that it compromises the ability of antigen\dependent T cells to proliferate